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Administration of PINK1 B9 flies with Mucuna puriens extracts resulted in increased GSH amount and SOD activity, together with restoration of mitochondrial morphology in crop muscles, olfactory response, climbing behavior, extended lifespan, and delay in L-DOPA induced long term motor complication 31,32,33

May 2017;22(3):5-7

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If the review period increases to 4 months and patients receive 4 or more injections within 1 year, instead of 6 or more, the savings are $15 million

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Titration is key: Gradual dose escalation maximizes tolerability