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Pre-conception planning should be discussed with a clinician before stopping contraception Mental health considerations : Some patients using GLP-1-based therapies have reported changes in mood

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Therefore, the functional capacity of adipose tissue is now recognized as a critical determinant of metabolic health in obesity [7], shifting the therapeutic focus from merely reducing fat mass to improving adipose tissue quality and function

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The gut microbiota metabolite capsiate regulate SLC2A1 expression by targeting HIF-1 to inhibit knee osteoarthritis-induced ferroptosis