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PSR and HE images were acquired with an Aperio VERSA 8 (Leica Biosystems), and immunofluorescence and WGA images were acquired with an Olympus BX53

How Vitamin B12 May Affect Your Skin The proposed mechanism by which vitamin B12 influences acne development involves the skin microbiome, particularly the bacterium Cutibacterium acnes (formerly Propionibacterium acnes ), which naturally resides in hair follicles and sebaceous glands