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10.1056/NEJMoa1307684 172 SestiG.AvogaroA.BelcastroS.BonoraB

Phase 3 outcomes will be critical to confirm sustained efficacy, cardiovascular benefit, tolerability at scale, and real-world adherence

Promotes fat loss and body recomposition

This causes several immune cells to be triggered, such as dendritic cells, macrophages, neutrophils, monocytes, and natural killer cells (142)

Protein expression is regulated at multiple levels, including post-transcriptional and post-translational levels [32,33,34,35]