What youll learn: Lemme Reset is a supplement that claims to support GLP-1, a hormone related to fullness and targeted by weight loss medications
Second Natures peer-reviewed study published in JMIR Formative Research (2025) compared both medications within our programme: 3 Tirzepatide (Mounjaro) cohort (209 people): 22.1% average weight loss at 12 months 95.2% achieved at least 10% weight loss 83.7% achieved at least 15% weight loss Semaglutide (Wegovy) cohort (130 people): 17.1% average weight loss at 12 months 83.1% achieved at least 10% weight loss 56.2% achieved at least 15% weight loss Both cohorts exceeded clinical trial results, suggesting that comprehensive behavioural support enhances outcomes regardless of which medication you use
You stare at the pen a little longer than necessary, reread the instructions for use twice, and wonder if you are about to pick the wrong injection site
Glutathione shows slow improvements to skin, having been shown to help correct dark spots and negative tone as well as protect against oxidative stress rather than using a sudden whiteness effect
Ethics declarations Competing interests SJW is the founder of Ridgeline Therapeutics, HN is a paid employee of Ridgeline Therapeutics and, since manuscript submission, ADW has also become a paid employee of Ridgeline Therapeutics
While psyllium husk can be a helpful tool for managing digestive discomfort, using it correctly is essential for both safety and effectiveness
