Available from: Sedatives and/or anesthetics may be used If necessary, a relaxation medication may be given through an intravenous (IV) line in the patients arm, but the patient is usually conscious during this procedure
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Nevertheless, studies utilizing more specific biomarkers of vitamin B 12 status, including measures of holo-transcobalamin and methylmalonic acid, have shown more consistent results and a trend towards associations between poor vitamin B 12 status and faster cognitive decline and increased risk of Alzheimers disease (82-86)
The driver may be systemic or involve a different pathway, including mast-cell activation
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MRI showed diffuse periventricular white matter changes (see figure 1AC)
