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SNRI = serotonin noradrenalin reuptake inhibitor

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They found that the combination of these growth factors displayed a more significant maximum load and tensile stress and inhibited scar formation compared to the IGF-1 alone group, suggesting that combination of IGF-1 and TGF- is more effective than IGF-1 alone in the treatment of tendon injury ( Moreover, the efficacy of IGF-1 therapy can be influenced by factors such as age, health conditions, and injury type

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The resulting consensus provides an integrated synthesis of available evidence, incorporating data from RCTs, systematic reviews, meta-analyses, in vitro , and animal studies