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Preclinical data also associate this signaling activity with lipolytic effects the mobilization of stored fat for use as an energy substrate which is one reason the compound appears in research examining body composition and metabolic regulation rather than muscle biology alone, a research area covered in more depth in our overview of the best peptides for fat loss

The peptide backbone of these compounds tends to undergo degradation in the infant gastrointestinal tract, further limiting systemic absorption if any traces enter breast milk