Important Context While the preclinical data is extensive and promising, it is essential to note that BPC-157 has not been evaluated in large-scale, randomized controlled human trials
Front Neurosci 12:214 Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E, Basavarajappa D, Radmark O, Kobayashi S, Seibt T, Beck H, Neff F, Esposito I, Wanke R, Forster H, Yefremova O, Heinrichmeyer M, Bornkamm GW, Geissler EK, Thomas SB, Stockwell BR, O'Donnell VB, Kagan VE, Schick JA, Conrad M (2014) Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
doi: 10.1089/thy.2018.0018 129 RenaudCOZirosPGChartoumpekisDVBongiovanniMSykiotisGP
Currently, theyre only indicated for diabetes, weight loss, and the prevention of major adverse cardiac events in patients who have atherosclerotic cardiovascular diseasebut the research shows significant benefit in chronic kidney disease, so I think thats probably on the horizon
B12 can help build the blood in patients with anemia, and it can help restore the blood in patients who are suffering from less than perfectly functioning kidneys
Metabolic rate changes may also play a role
