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Additionally, Trem2 serves as a transmembrane molecule found in hepatic macrophages originating from both bone marrow and embryonic sources

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Clinically, liver injury manifests as a sharp rise in transaminases, abnormal bilirubin metabolism, and coagulation dysfunction, often combined with damage to the heart, brain, kidneys, and other organs, constituting MODS

Europ J Pharmacol 1990, 186: 17780

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