The dual mechanism of Mounjaro not only enhances glycemic control but also has implications for cardiovascular health
Worsening neurological symptoms : Progressive weakness, worsening balance problems, or deteriorating cognitive function despite treatment requires urgent assessment
Blackman A, Foster GD, Zammit G, Rosenberg R, Aronne L, Wadden T et al (2016) Effect of liraglutide 3.0 mg in individuals with obesity and moderate or severe obstructive sleep apnea: the SCALE Sleep Apnea randomized clinical trial
Treatment duration, dosage, and method should be carefully considered
McDougal, a FDA/CDER nonclinical reviewer, specific safety concerns for mAbs include cross-reactivity, slow elimination, exaggerated pharmacology, and slow recovery from toxicity
We can only speculate on the underlying mechanisms, but it is possible that females overall preserve energy more efficiently as evidenced by earlier reductions in body temperature shown here and preserved visceral fat, despite the caloric deficit in PF rats
