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Bioavailability is a critical measure in pharmacology, indicating how much of a given dose of a drug is available to produce a therapeutic effect

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Therefore, DPP-4 inhibitors extend the half-life of endogenous GLP-1 lead to a 2threefold elevation of endogenous GLP-1 concentration, and provide beneficial effects in T2DM [110, 111]

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patients must understand they are receiving a medication outside its FDA-approved indication

Youve likely seen the ads and social media posts about weight loss pills, patches and shots many claiming to include GLP-1 medications and all professing to be the solution to losing extra pounds