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10.7554/eLife.02523 23 DonovanJ.DengZ.BianF.ShuklaS.Gomez-ArroyoJ.ShiD.et al (2023)

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Reducing glutathione production in lymphoma cells, either through pharmacological inhibition of glutamate cysteine ligase (GCL), the enzyme catalyzing the rate-limiting step in glutathione biosynthesis, or via knockdown of GCLC , the GCL catalytic subunit, sharply decreased cell growth in 3D gels and xenografts

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Unlike other GH-releasing peptides (GHRPs) like CJC-1295 and Ipamorelin, which stimulate the pituitary gland to release more hGH, AOD-9604 works independently of natural hGH secretion

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