Semaglutide trials have shown average body weight reductions of 1520%+ over 68 weeks
Salem ME, Andre T, El-Refai SM, Kopetz S , Tabernero J, Sinicrope FA, Tie J, George TJ, VanCutsem E, Mauer E, Lonardi S, Overman MJ, Foureau D
(September 2018)
doi: 10.21037/atm-21-6942 91 BezerraFSLanzettiMNesiRTNagatoACSilvaCPEKennedy-FeitosaEet al
Vitamin B12 absorption occurs primarily in the terminal ileum through intrinsic factor-mediated absorption (for both dietary and supplemental B12) and passive diffusion (particularly relevant for high-dose supplements)
To further complicate matters, the study states: "no clear optimal [pH range] was seen when the test was run without [fatty acid byproduct]." It was only used to compare how animal and human skin metabolises the form of vitamin A naturally present in the skin, not about how topical vitamin A (retinol) benefits the skin