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In this Review, we highlight the latest advances in our understanding of the mechanisms of action of metformin and discuss potential emerging novel therapeutic uses

Sulforaphane is produced when the plant is damaged when attacked by insects or eaten by humans

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Any use outside approved indications would be considered off-label prescribing, which requires careful clinical justification and informed patient consent

however, levels under 350 pg/mL are known to be associated with neurological symptoms