The 2012 New England Compounding Center outbreak documented what happens when even professional compounding environments fall short of sterility standards contaminated injectable methylprednisolone resulted in 751 fungal infections and 64 deaths across 20 states
Annual Review of Pathology
General wellness falls somewhere in between
After 24 weeks, mean decreases from baseline of -2.9% for A1C, -127 mg/dL for FPG, and -208 mg/dL for 2-hour PPG were observed
Abbreviations 1 O 2 : Singlet oxygen ADP: Adenosine diphosphate AOX: Alternative oxidase APX: Ascorbate peroxidase Asc: Ascorbate ATP: Adenosine triphosphate cat : Catalase knockout CAT: Catalase chl- E : GSH Chl-roGFP oxidation state chl-roGFP2: Chloroplast targeted roGFP CLSM: Confocal-laser scanning microscopy cry: Cryptochrome DTT: Dithiotreitol E : h Reduction potential ER: Endoplasmic reticulum FIN219: Far-Red Insensitive 219 FIP1: FIN219-interacting protein 1 GGT-1: Gamma-glutamyl transferase/transpeptidase 1 ggt : GGT-1 knockout GR: Glutathione reductase GSH: Reduced glutathione GSHS: Glutathione synthetase GSSG: Oxidized glutathione (= glutathione disulfide) GSSG/GSH: Reduction state of glutathione GT: Glutathione transferase H 2 O 2 : Hydrogen peroxide HPLC: High performance liquid chromatography HyPer2: Fluorescent H 2 O 2 biosensor IgG: Immunoglobulin G immunolabeling: Total glutathione localization by use of a specific antibody LEDs: Light-emitting diodes mbrB: Monobromobimane mchlB: Monochlorobimane NADP + : Nicotinamide adenine dinucleotide phosphate NADPH: Reduced form of NADP + NEM: N-ethylmaleimide O 2 : Superoxide radicals pad : Phytoalexin deficient phyA: Phytochrome A PS II: Photosystem II roGFP: Redox-sensitive green fluorescence protein ROS: Reactive oxygen species SOD: Superoxide dismutase TEM: Transmission electron microscope Total glutathione: Sum of reduced (GSH) and oxidized (GSSG) glutathione, detected via immuno-labeling vtc : Vitamin C1 gene -EC: -Glutamylcysteine -ECS: -Glutamylcysteine synthetase References Appolloni E, Pennisi G, Zauli I, Carotti L, Paucek I, Quaini S, Orsini F, Gianquinto G (2022) Beyond vegetables: effects of indoor LED light on specialized metabolite biosynthesis in medicinal and aromatic plants, edible flowers, and microgreens
The drug identification number (DIN) is easy to find
