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A meta-analysis by Faraone and Buitelaar (2010) pooling data from multiple randomized controlled trials found that amphetamine-based medications had a modestly larger mean effect size (SMD 0.99) for ADHD symptom reduction compared to methylphenidate-based medications (SMD 0.78) [6]

Weina H, Yuhu N, Christian H, Birong L, Feiyu S, Le W

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Common side effects include: Nausea and vomiting Digestive issues like diarrhoea, constipation, or abdominal pain Headaches and fatigue Injection site reactions Serious but less common side effects: Pancreatitis Gallbladder problems Kidney problems Low blood sugar Most gastrointestinal side effects settle within the first month or two