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Report any suspected side effects to the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk

Since GLP-1 receptor agonists are relatively new, long-term studies on their effects during pregnancy are still ongoing

We observed that GLP-1MK-801 has similar receptor signalling properties at the GLP-1 receptor compared to the parent GLP-1 analogue as well as to the pharmacokinetically optimized GLP-1 receptor agonists semaglutide and liraglutide (Extended Data Fig

Superposition of PF-06372222-bound crystal structure (containing the C347 6.36b F mutation), with crystal structure based molecular dynamic simulations of F347 shown in blue (500 ns) and of simulations C347 (6.36b mutated back to cysteine) shown in pink (500 ns)

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