Although diabetes incidence showed only a modest increase in all mice, the study found a significant acceleration of T1D onset in females and an increase in insulitis in males (114)
Clinical studies across multiple patient groups have shown that AOD 9604 does not raise blood sugar, trigger excessive hunger, or affect cortisol levelsmaking it easier for patients to stay consistent with their weight loss goals
Additionally, PT in ewes is associated with maternal hypoglycemia (Iqbal et al., 2022) and increased triglyceride levels (Turgut et al., 2025b)
The studies conducted on this topic suggest that allowing the body to use fat as a source of energy can lead to increased endurance since it is less glycogen dependent and fat utilization is improved
Glutathione Study
Now that Tylenol is making headlines, its a good time to look at the bigger picture: frequent use, combined with other daily factors that deplete glutathione, can add to the bodys oxidative load and impact liver and overall cellular health