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Influence of Exercise Increases in muscle carnosine content have been hypothesized to be an adaptation to long-term high-intensity training as demonstrated by higher values in bodybuilders ( Despite cross-sectional data suggesting an adaptive role of muscle carnosine in response to training, most short-term (416 weeks) exercise training protocols have, however, failed to modify intramuscular carnosine content ( Despite clear evidence that exercise can influence muscle carnosine homeostasis ( 1 despite the athletes not being put through a specific training protocol ( Co-supplementation of Histidine With Beta-Alanine Carnosine is formed by BA with L-histidine and is therefore dependent on the availability of both of these amino acids ( Current Recommendations and Future Investigation Chronic BA supplementation increases the intracellular content of carnosine in skeletal muscle and can subsequently improve sports and exercise performance

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doi: 10.1038/srep29094 116 PrinsterACantoneEVerlezzaVMagliuloMSarnelliGIengoMet al

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