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However, it requires conversion in the liver to methylcobalamin and adenosylcobalamin before it can be used in enzymatic reactions

Long-read genome sequencing could facilitate the discovery of additional SLOCA-causing gene variants, and validation of surrogate biomarkers would promote the identification of disease-modifying drugs

Similarly, Fgf21 -KO mice also exhibited a significant attenuation of weight loss (Extended Data Fig

Forgione and colleagues previously hypothesized that GPX1 deficiency caused an increase in vascular oxidative stress with endothelial dysfunction directly involved [57]

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