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Calcium- and activity-dependent synaptic plasticity

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ISSN 0007-9235

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This resulted in a reduction of the turnover number to 1.40.4, which, in the absence of thermal deactivation (see below), indicated that the [C-RML][ S 1 ] conjugate could use the limited number of water molecules to complete the reaction cycle via nucleophilic addition to the acylated enzyme intermediate

( a ) A Ligplot+ v2.2 diagram of the N-terminal interacting residues of Ex-4-D-Ala bound to GLP-1R as observed in the conformer 1 model