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(2024) 10:e35114

10.1146/annurev.publhealth.28.021406.144007 218 NguyenA.RauchT

If the vial has been in use for more than 28 days, it is not to be administered anymore and should be discarded immediately

Lee J, Hong EM, Kim JH, Jung JH, Park SW, Koh DH, Choi MH, Jang HJ, Kae SH (2019) Metformin induces apoptosis and inhibits proliferation through the AMP-activated protein kinase and insulin-like growth factor 1 receptor pathways in the bile duct cancer cells

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Sublingual B12, which bypasses the gastrointestinal tract, is the least invasive and potentially most cost-effective option, especially for individuals with impaired absorption, making it an attractive alternative for long-term and patient-friendly management (Houle et al., 2014