Unpredictable Results : The same prebiotic can produce vastly different outcomes in different people, making it difficult to predict who will benefit and who won't
The results showed that compared to a placebo, the combined reduction in the risk of kidney failure, worsening kidney function, and death due to kidney disease was 19%
boulardii is the most evidence-backed probiotic for diarrhea management, period
References: GLP-1 Agonists Can Affect Mood: A Case of Worsened Depression on Ozempic (Semaglutide) - ( GLP-1 Receptor Agonists in Mood Disorders - ( GLP-1 Receptor Agonist Semaglutide Reduces Appetite While Increasing Dopamine Reward Signaling - ( Risk of Depression with GLP-1 Receptor Agonist Use in Overweight or Obese Adults with Type 2 Diabetes - ( Beyond Weight Loss: GLP-1 Usage and Appetite Regulation in the Context of Eating Disorders and Psychosocial Processes - ( Glucagon-like Peptide-1 Medicines in Neurological and Psychiatric Disorders - ( Source-Medindia
Short-term GLP-1 side effects include nausea, constipation, and reflux, and many individuals stop use due to the constant GI issues
Prof Alexander Miras, an obesity expert at Ulster University who was not involved in the work, described the findings as very important, noting that while GLP-1s had been associated with improved functionality meaning it was easier to carry out everyday activities they had also been associated with a loss in muscle mass and strength