Long-term potentiation (LTP), which Dihexa enhances, has been shown to stimulate proliferation of progenitor cells in the dentate gyrus and promote survival of newly born neurons, suggesting Dihexa may facilitate neural regeneration through multiple complementary mechanisms
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Here's the mechanism: the enzyme ALDH2 (aldehyde dehydrogenase 2) oxidises acetaldehyde into acetic acid, but this process requires adequate glutathione reserves to neutralise reactive oxygen species (ROS) generated during the reaction
in smoking models, it inhibits JNK/p38 MAPK to reduce caspase-3 activation and myocyte apoptosis (Zhou et al., 2014)
More information The American Academy of Sleep Medicine has more on sleep apnea
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