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Int J Biochem Cell Biol 41(10):20512061 Mats JM, Segura JA, Martn-Rufin M, Campos-Sandoval JA, Alonso FJ, Mrquez J (2013) Glutaminase isoenzymes as key regulators in metabolic and oxidative stress against cancer
In DM1, steady-state levels of CELF1 protein are increased due to hyperphosphorylation 7 , and MBNL proteins functionally depleted due to sequestration by CUG exp RNA 6
Pernicious anaemia , an autoimmune condition affecting approximately 2% of the UK population over 60 (and about 0.10.2% overall), destroys gastric parietal cells, eliminating intrinsic factor production and severely impairing B12 absorption
Drugmakers are tackling these diseases through varied approaches, from repurposing existing drugs to developing sensory stimulation headsets