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In this study, we aimed to determine the prevalence of thyroid-related autoantibodies in patients with primary hypothyroidism and to evaluate the differences in thyroid structure between antibody-positive and antibody-negative hypothyroidism

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Abbreviations AMPK: AMP-activated protein kinase CNS: Central nervous system DIO: Diet-induced obesity FGF21: Fibroblast growth factor 21 GCGR: Glucagon receptor GIP: Glucose-dependent insulinotropic polypeptide GLP-1: Glucagon-like peptide 1 K ATP channel: ATP-sensitive potassium channel MBH: Mediobasal hypothalamus NAFLD: Non-alcoholic fatty liver disease PKA: Protein kinase A STZ: Streptozotocin References Banting FG, Best CH, Collip JB, Campbell WR, Fletcher AA (1922) Pancreatic extracts in the treatment of diabetes mellitus

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