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The article says individual response to a specific semaglutide dose depends on baseline receptor sensitivity, metabolic rate, and kidney function, and that some patients achieve therapeutic benefit at lower doses while others need more to reach target outcomes
In a first part, I discuss biological issues related to the persistence of microbial antigens, dysregulated immune responses, reactivation of latent viruses, different potential self-sustained inflammatory loops, mitochondrial dysfunction, metabolic disorders in the tryptophan- kynurenin pathway (TKP) with impact on serotonin, and consequences of a dysfunctional bidirectional microbiota-gut-brain axis
Clinicians may provide guidance on follow-up or future sessions if appropriate
Most users notice reduced appetite within days to weeks of starting treatment