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Discontinue use and seek professional advice if significant irritation or an allergic reaction occurs

Additionally, notoginsenoside R1 has been reported to improve microvascular endothelial function in animal models of hypertension, partly by reducing inflammation (e.g., lowering VCAM-1 expression as noted earlier)

This appears to be largely mediated through improvements in insulin sensitivity and weight loss, which reduce androgen excess and normalise hypothalamic-pituitary signalling

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Metabolic Effects of Probiotics for PCOS lower blood sugar levels reduced HOMA-IR (insulin resistance) was reduced reduced weight reduced fasting insulin reduced triglycerides

In the same study, elevated levels of serum lncRNA MALAT1 predicted worse clinical outcomes in OS patients