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Angiogenesis, the formation of the arteries by the development of pre-existed parental blood vessels, is a phenomenon that occurs naturally during puberty due to certain physiological processes such as menstruation, wound healing, or the adaptation of athletes bodies during exercise

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246 For example, SMAD2 ubiquitination by Itch/AIP4 promotes its phosphorylation by TRI, facilitating signal transduction

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