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Similar findings are reported of gut microbes as changes in their composition are associated with CKD

In plasma and serum, markers of coagulation (increased), complement (decreased), and fibrinolysis (increased and decreased) showed changes relative to HC (Gkouvi et al., 2024)

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A deficiency of acid phosphatase activity in the lysosomal fraction, presumably due to impairment of the ACP2 protein, manifests as intermittent vomiting, hypotonia, lethargy, opisthotonos, terminal bleeding and death in early infancy (136)

In this regard, HEK cells represent a robust cell line with a broad range of applications, e.g

Might be worth asking your doctors if they have checked your iron levels