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The oral semaglutide dose was escalated from 5 mg during the first 5 days to 10 mg during the last 5 days in order to mitigate the risk of gastrointestinal adverse events (AEs)

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15,57 Notably, liraglutide exhibits relatively clear anti-fibrotic effects among GLP-1RAs, although statistically significant improvements in fibrosis were not observed in clinical trials

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Sanofi developed Toujeo as the next generation of their insulin glargine line

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