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Description GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring copper-binding tripeptide first identified in human plasma

10.31925/farmacia.2021.6.10 Farmacia 44 GivlerD.GivlerA.LutherP.WengerD.AhmadzadehS.ShekoohiS.et al (2023)

The GHRL is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques

Furthermore, these findings open the door to investigating additional pathways, such as the G protein-coupled estrogen receptor (GPER)

Stability and Handling# Dihexa is relatively stable due to its non-natural modifications (N-hexanoic acid cap, aminohexanoic amide C-terminus), which protect it from typical peptidase degradation