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Conclusion: This analysis showed a high overall burden of disease among those with non-cirrhotic MASH, compensated MASH cirrhosis and decompensated MASH cirrhosis
Therefore, an imbalance in the production and clearance of the A protein is a key part of AD pathology
This ripple effect extends beyond pharma to food and beverage companies investing in GLP-1 friendly products
Secondary endpoints included changes in total alcohol consumption, number of days without alcohol, number of drinks per drinking day, and craving, among others (these included various metabolic measures and biomarkers)
Anti-Inflammatory Effects: GLP-1 RAs exhibit broad anti-inflammatory properties, reducing oxidative stress and the expression of pro-inflammatory cytokines (e.g., TNF-, IL-6) by inhibiting the NF-B signaling pathway