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Confocal imaging Tyrosine hydroxylase (TH)-Gal4 driven UAS-GFP lines, labeling the neurons with active dopamine synthesis pathway, were crossed with park 13 flies and progenies were exposed to Sp from 10 days AEL

In a randomized phase II trial involving patients with metastatic or locally advanced chondrosarcoma, IPI-926 failed to demonstrate improvements in progression-free or overall survival compared with placebo, despite good tolerability

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doi: 10.1124/jpet.108.140533

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