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Participants with normal hepatic function were eligible for inclusion if they were judged to be of general good health by the investigator, based on a medical examination (including physical examination, medical history, vital signs and ECG) and had liver enzyme levels within prespecified limits (alanine aminotransferase upper limit of normal [ULN] + 10%, aspartate aminotransferase ULN + 20% and total bilirubin ULN + 20%)

Semaglutide is easy to administer and can be taken at any time of the day with or without food

doi: 10.1016/j.annonc.2022.02.004

In patients with GD, an inverse relationship of serum Se levels with T4 and TSH hormones and an inverse relationship with T3, T4, and TSH hormones were found in patients with GO, although there was no significant difference in Se levels in patients compared to healthy individuals (70)

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