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doi: 10.1053/j.jrn.2017.02.010 101

People with MTHFR mutations almost always have low glutathione levels, making them more susceptible to stress and oxidative stress while making them far less tolerant to toxins

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Inhibition of oral peroxidase activity by cigarette smoke: in vivo and in vitro studies

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Interactions and contraindications [edit] Taking SAM at the same time as some drugs may increase the risk of serotonin syndrome, a potentially dangerous condition caused by having too much serotonin