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In another study, infusion of GLP1 rescued rats from aging-related declines in insulin secretion and glucose tolerance

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Patients who maintain their results beyond 12 weeks are those who adjusted caloric intake downward as weight decreased, incorporated refeed days to manage leptin suppression, and understood that the injections support the process but don't override thermodynamics

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If confirmed in larger studies, this could influence long-term dosing strategies and improve treatment sustainability