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The tests are usually ordered for patients prior to surgery to ensure normal clotting ability
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The BEACON trial was a phase 3 double-blinded, placebo-controlled trial in individuals with stage 4 diabetic kidney disease (eGFR range 1529 mL/min/1.73 m 2 ) designed to test the hypothesis that bardoxolone methyl would reduce the risk of end-stage kidney disease or death from cardiovascular causes in these patients [57]
