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1 AHK-Cu and GHK-Cu are close chemical cousins (they differ in the first residue, alanine versus glycine), and they share the copper-binding motif that gives the family its character

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Adapted from [19]

10.1016/j.mam.2018.02.001 81 JayD.HitomiH.GriendlingK

Moreover, proteomic profiling revealed that the NP/OXA-ASP synergistically combated tumors through a triple-barreled mechanism of metabolic suppression, apoptosis induction, and immune activation, rather than operating via single-target effects (Fig