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Metformin is usually the first-line medication for type 2 diabetes because it's effective, affordable, and well-tolerated by most people

Glucotoxicity and cell dysfunction: involvement of the PI3K/Akt pathway in glucose-induced insulin resistance in rat islets and clonal TC1-6 cells

It is the manufacturer of tirzepatide, also known as Zepbound and Mounjaro, a drug that has seemingly unmatched potential when it comes to weight loss

Dose titration over several weeks minimises side effects and delays maximum therapeutic effects until maintenance dose is reached

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10.1080/13510002.2024.2398380 239 XiaC.TaoY.LiM.CheT.QuJ