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Respiratory Exposure to Copper Oxide Particles Causes Multiple Organ Injuries via Oxidative Stress in a Rat Model

It halts the activation of Tyrosinase which produces melanin

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However, when treated with the supersulfide donor NAC-S2, the survival rate increased to 90% and ameliorated inflammatory responses, such as reduced TNF- production

It could be a sensitivity or a paradoxical reaction if their detoxification pathways are congested (including the interstitium and liver)

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