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Third, CON was not provided a placebo supplement, and was involved only in the training protocol, which made this study partially blinded

While the compounds structure is undisclosed, it is described to have potent activity on hMC4R in a functional cAMP assay (EC 50 = 2 nM, E max = 95%), inactivity on hMC3R, and reduced potency on hMC1R (25, 136)

Most trials are randomized and blinded, meaning some participants receive retatrutide, while others get a placebo that doesnt include the active ingredients

A committee recommendation is advisory and not binding

Such effect was not observed in elder women (age range 6570 y.o.) after a similar period of supplementation [15]