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Decreasing neck and abdominal adiposity directly reduces mechanical airway resistance, a key factor in OSAS pathogenesis (38, 49)

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In the central nervous system, the action of GLP-1 and GLP-1RAs on its receptors can affect a variety of brain functions including satiety, thermogenesis, influence blood pressure, neurogenesis, neurodegeneration, retinal repair, and change energy homeostasis [16-20]

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