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This article examines the historical evolution of medication-assisted treatment (MAT), explores current options, breaks down barriers to access and compliance, and previews promising new pharmacotherapies that could redefine addiction treatment in the years ahead

Use each vial within its intended window rather than treating an opened vial as something you can keep indefinitely

The glial glutamate transporter 1 (GLT1) is expressed by pancreatic beta-cells and prevents glutamate-induced beta-cell death

Without human trials, clinicians cannot reliably determine appropriate dosing, long-term risks or whether benefits outweigh risks

Foundayo (orforglipron), developed by Eli Lilly, is a new, once-daily oral GLP-1 weight-loss pill approved in the UAE (second globally after the US) and expected to be available from May 2026