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The contents of the vial are mixed gently with the diluent (avoiding shaking, which can denature the peptide) until fully dissolved

It is not found in nature in its isolated form but is derived from a larger protective protein present in gastric secretions

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The study used databases at the Toronto-based Institute for Clinical Evaluative Sciences to review the patient records of 146,850 residents of the province aged 65 or over who were prescribed regular vitamin B12 shot between January 2011 and October 2015

The form of B12 used can affect the cost as well