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Although it has been generally accepted that the development of endometriosis is closely associated with hormones, inflammation, dysfunctional immunity, oxidative stress, genetic and epigenetic factors as well as environmental factors, the pathogenesis of endometriosis has not been completely elucidated [4]
Clinical studies have shown oral semaglutide to have superior efficacy to placebo and to a number of oral and injectable active comparators representative of common drug classes (DPP-4 inhibitors, other GLP-1RAs, SGLT2is), with a safety and tolerability profile consistent with the GLP-1RA class
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GLP-1 receptor agonists and renal outcomes in patients with diabetes mellitus type 2 and diabetic kidney disease: State of the art