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For women using estrogen-containing or progestin-only oral contraceptives, Topiramate may reduce contraceptive efficacy

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Reducing some symptoms associated with irregular cycles in some women

42-44,124,133 Oral Appliances Oral appliances, the most common of which is the mandibular advancement device (MAD), are used during sleep to physically keep the upper airway open by either holding the lower jaw forward or moving the tongue forward

Other Medications: Certain central nervous system medications used in GH stimulation tests, for example, dopamine agonists (like L-Dopa) or arginine, can affect GH release

Serious safety concerns (immune reactions, cancer risk)