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First, lack of exposure is possible, as we lacked information on patient compliance with prescribed treatments and potential lack of medication dispensed at hospitals, however as medication compliance is similar across all three groups and we defined exposure as redeemed prescriptions, ensuring that the medication was actively collected by the patient, systematic misclassification is unlikely
N Engl J Med 2025;Mar 29:[Epub ahead of print].
Shared decision-making between patient and provider should guide therapeutic adjustments, balancing metabolic benefits against tolerability concerns