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Collectively, these findings suggest that FGF21 may mediate some of the beneficial effects of exercise on atherosclerosis, particularly through the PI3K/AKT signaling pathway and anti-apoptotic mechanisms

Appetite regulation: Recent studies have shown that Ozempic acts on the brain's appetite, reducing hunger and cravings

Prospective clinical trials demonstrated that oral semaglutide significantly reduced body weight and glycated hemoglobin (HbA1c) in more than 9,500 patients with T2D

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Similarly, recent long-term studies of liraglutide and semaglutide, focusing on cardiovascular outcomes in individuals with type 2 diabetes, reveal a similar incidence of pancreatitis between groups treated with the GLP-1R agonists and placebo [31, 41]

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